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Dear reader, between 1966 and 1969, a hospital in Boston treated seven young women for a cancer of the vagina. That sentence should not be possible. Clear cell adenocarcinoma of the vagina is so rare that a gynecologist may practice forty years without seeing one, and when it appears, it appears in women past middle age. These patients were between 15 and 22 years old. An eighth case followed. All had been born in New England hospitals between 1946 and 1951.

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